Considerations To Know About PLH2058
Considerations To Know About PLH2058
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Use of the next concomitant medications (Call the Sponsor-specified healthcare monitor to find out eligibility when in doubt):
will not likely or can't cooperate with ophthalmic evaluation demanding pupillary dilation (incorporates history of significant adverse response to mydriatic brokers or untreated slender angle glaucoma).
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Perifosine is often a artificial antitumor alkylphospholipid. It induces cell apoptosis through inhibiting the action of Akt. Perifosine shows antitumor action in various cell strains like NSCLC, MM, epithelial carcinoma, prostate carcinoma and leukemia cells. In H460 cells, perifosine reduced mobile survival and induced apoptosis with IC50 values of oneμM L-692429 and 10 μM, respectively.
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